Robert W. Stackman, Jr.
Ph.D., Rutgers, The State University of New Jersey
Postdoctoral Fellow, Dartmouth College
- Cellular and circuit mechanisms of long-term memory
- Spatial navigation and limbic system networks
- Behavioral (in-vivo) neurophysiology
- Hippocampal and cortical interactions and coding of object memory
Research in our lab focuses on a number of related projects seeking to understand the brain circuitry that supports long-term memory in mammals. The work follows an overarching hypothesis that individual significant experiences or events are organized in the nervous system as memories about objects and the context where they were experienced. Fundamental to the organization of such event memories is the integration of parallel streams of information within the hippocampus or the broader hippocampal formation. One project explores the contribution of specific cortical regions to memory for objects and context. Another project maps neurons, within regions of the memory circuit, which encode attributes of memory. Another project examines the degree to which neurons coding spatial location and directional heading, guide spatial problem solving. Another project examines SK-type potassium channel influence on behavior and behaviorally-triggered synaptic plasticity. Taken together, these projects will provide novel insights into memory organization and how neurophysiological representations of memory attributes guide memory retrieval and problem solving.
- Zhang, G., Cinalli Jr., D. and Stackman Jr, R.W. (2017). Effect of a hallucinogenic serotonin 5-HT2A receptor agonist on visually-guided hippocampal-dependent spatial cognition in C57BL/6J mice. Hippocampus,
Stackman Jr, R.W., Cohen, S.J., Lora, J.C., and Rios, L.M. (2016). Temporary inactivation reveals that the CA1 region of the dorsal hippocampus plays an equivalent role in the retrieval of long-term object memory and spatial memory. Neurobiology of
Learning and Memory,
- Cohen, S.J. and Stackman Jr, R.W. (2015). Assessing rodent hippocampal involvement in the novel object recognition task. A review. Behavioural Brain Research,
- Cohen S.J., Munchow, A., Rios, L.M., Zhang, G., Ásgeirsdóttir, H.N. and Stackman Jr, R.W. (2013). The rodent hippocampus is essential for non-spatial object memory. Current Biology.
Stackman, R.W. Lora, J.C. and Williams, S.B. (2012). Directional responding of C57BL/6J mice in the Morris water maze is influenced by visual and vestibular cues and is dependent upon the anterior thalamic nuclei. Journal of Neuroscience.